Brigham and Women’s Hospital
Gad Marshall, MD
Site PI
Dr. Gad Marshall received his undergraduate and medical degree from Boston University. He then completed a neurology residency at the University of Pittsburgh, followed by a dementia and behavioral neuroscience fellowship at the University of California, Los Angeles. He is board certified in Neurology and the current Director of Clinical Trials at the Center for Alzheimer Research and Treatment at Brigham and Women’s Hospital; Associate Neurologist at Brigham and Women’s Hospital; Assistant in Neurology at Massachusetts General Hospital; and Associate Professor of Neurology at Harvard Medical School. Over the past 20 years, he has focused on improving the clinical care of patients with Alzheimer’s disease (AD) and related conditions, in conjunction with clinical research in AD. Over the past 17 years, he has been site principal investigator for 14 clinical trials and 4 observational imaging studies in AD such as the Alzheimer’s Disease Neuroimaging Initiative (ADNI). His NIH-funded research has focused on clinical correlates of instrumental activities of daily living and neuropsychiatric symptoms with amyloid, tau, and FDG PET, structural and resting-state functional MRI, across the early AD spectrum. More recently, he has been developing novel sensitive performance-based instrumental activities of daily living tests for early-stage AD. He is also co-principal investigator for an NIH-funded proof-of-concept clinical trial of a sirtuin-NAD+ activator in AD. Moreover, he has been a Steering Committee Member and Chair of the Publications Committee of the Alzheimer’s Clinical Trial Consortium (ACTC) since its inception in 2018, as well as a Mentor for the Early Career Project Evaluation Committee of ACTC since 2020.
Scott McGinnis, MD
Site Co-PI
Seth Gale, MD
Site Co-PI
Seth Gale, MD is a behavioral neurologist at Brigham and Women’s Hospital (BWH) and Assistant Professor of Neurology at Harvard Medical School. He is Co-Director of the Brain Health Program at BWH and works as an investigator in Alzheimer disease at the Center for Alzheimer Research and Treatment (CART). Dr. Gale’s research interest is in lifestyle and non-pharmacologic interventions, including use of mobile technology platforms, to promote brain health and reduce the risk of cognitive decline. He is also interested in the ethics and philosophy of medicine.
Danielle Lavey
Site Liaison
Martha Muniz
Community Engagement Specialist
Martha Muniz has been with the CART team for 9 years, driven by a personal connection to Alzheimer’s through her grandmother. As Director of Recruitment and Community Engagement Specialist, she focuses on improving representation in clinical trials and raising awareness about the impact of research on Alzheimer’s. Martha enjoys using her creativity to enhance operations, engagement strategies, and mentor new team members.