Alzheimer's Clinical Trials Consortium

Early-Career Project Evaluation Committee

Athene Lee, PhD

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Dr. Athene Lee is an Assistant Professor in the Department of Psychiatry and Human Behavior at Brown University Alpert Medical School. She is also a clinical neuropsychologist at the Butler Hospital Memory and Aging Program and the Director of the Butler Alzheimer’s Prevention Registry. Dr. Lee is a site principal investigator for the Trial-Ready Cohort for Preclinical/Prodromal AD (TRC-PAD), site neuropsychologist for the U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk (U.S. POINTER), and sub-investigator for several other Alzheimer’s disease clinical trials. At the Alzheimer’s Clinical Trial Consortium (ACTC), Dr. Lee serves as the founding Chair of the Early Career Project Evaluation Committee, a Co-Vice Chair of the Inclusion, Diversity and Education in Alzheimer’s disease – Clinical Trials (IDEA-CT) Committee, and the Butler Hospital Site Associate Principal Investigator. Dr. Lee received her doctoral degree in clinical psychology from Suffolk University and completed her residency and fellowship in neuropsychology at Brown University Alpert Medical School. She is dedicated to promoting early identification and intervention for cognitive decline and to enhance diverse representation in Alzheimer’s disease and related dementia research. Her research is focused on risk prediction algorithm for preclinical Alzheimer’s disease, disclosure of genetic and biomarker risk for Alzheimer’s disease, and cultural influence on subjective cognitive decline.

Rema Raman, PhD

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Rema Raman, PhD, is a tenured Professor of Neurology at the Keck School of Medicine of the University of Southern California (USC), the Director of Biostatistics of USC’s Alzheimer’s Therapeutic Research Institute (ATRI), and the Director of the Biostatistics Unit for the Alzheimer’s Clinical Trials Consortium (ACTC).   Dr. Raman also serves as Co-Lead for the ACTC Recruitment, Engagement, and Retention Unit and Co-Chair of the Inclusion, Diversity and Education in Alzheimer’s disease – Clinical Trials (IDEA-CT) Unit. She is also Co-Chair of the Project Feasibility Committee. Dr. Raman received her training in biostatistics from the School of Public Health at the University of Illinois at Chicago. Her statistical research interests are in efficient clinical trial design and monitoring approaches (risk-based monitoring, data visualization), and correlated data analysis topics (impact of missing data, analysis of ordinal data). Dr. Raman has extensive experience as a biostatistician in biomedical research projects, providing biostatistics and data management leadership to the design, coordination, conduct and analyses of clinical trials and large observational studies. She has served or currently serves as the primary statistician for several, multi-center clinical trials in Alzheimer’s disease, acute stroke, post-traumatic stress disorder, and traumatic brain injury. She is a regular member of the NIH CNN study section, an ad-hoc member on several others and serves as the Biostatistician on several Data and Safety Monitoring Boards.