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Alzheimer's Clinical Trials Consortium

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Internal Ethics Committee

Jason Karlawish, MD

September 21, 2019 by

Jason Karlawish is a Professor of Medicine, Medical Ethics and Health Policy, and Neurology at Penn and cares for patients at the Penn Memory Center (www.pennmemorycenter.org), which he co-directs. He leads the ACTC Ethics Committee, is a member of the Recruitment and Retention Core and the Steering Committee. At Penn, he leads the Outreach and Recruitment Core and Research Education Component of the ADRC. His research focuses on issues at the intersections of bioethics, aging and the neurosciences. He leads the Penn Program for Precision Medicine for the Brain (P3MB). P3MB developed standards for Alzheimer’s disease biomarker disclosure and investigates the clinical impacts of this knowledge on persons and their families. He has investigated the development and translation of Alzheimer’s disease treatments and biomarker-based diagnostics, informed consent, quality of life, research and treatment decision making, and voting by persons with cognitive impairment and residents of long term care facilities.  P3MB developed the amyloid imaging disclosure process and the SOKRATES Study, originally used in the A4 Study, these have become a template for assuring the safe disclosure of Alzheimer’s disease genes and biomarkers and assessing their impact on persons and their families.

Joshua Grill, PhD

September 21, 2019 by

Joshua D. Grill, PhD, is an Associate Professor in the Departments of Psychiatry & Human Behavior and Neurobiology & Behavior at the University of California, Irvine (UCI). He is the Director of the Institute for Memory Impairments and Neurological Disorders (UCI MIND) and the Associate Director of the UCI Alzheimer’s Disease Research Center. He also directs its Outreach, Recruitment, and Engagement Core for the UCI ADRC and is the leader of the Accrual and Retention Consult Service for the UCI Institute for Clinical and Translational Science (ICTS). Dr. Grill serves in several roles for ACTC. He is co-leader of the Recruitment, Engagement, and Retention Unit as well as the Internal Ethics Committee. He also serves on the Executive and IDEA-CT Committees. Dr. Grill’s independent research is focused on clinical trial design, recruitment and retention, and research ethics across the spectrum of Alzheimer’s disease.

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      Alzheimer's Clinical Trials Consortium
      Alzheimer's Clinical Trials Consortium

      ACTC is funded by a Cooperative Agreement from the National Institute on Aging, National Institutes of Health.  Cooperative Agreement number U24AG057437.

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