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Clifford R. Jack Jr., M.D., is Co-Lead for the ACTC MRI Unit. Dr. Jack is engaged in brain imaging research in cognitive aging and Alzheimer's disease and related disorders.  Dr. Jack's research group employs imaging to study the biology of brain aging and cognitive impairment. They also develop image-processing algorithms for quantitatively measuring the information obtained from brain imaging. They employ a variety of brain imaging modalities including anatomic MRI, MR spectroscopy, functional connectivity MR, diffusion MR, perfusion MR, quantitative susceptibility mapping, FDG PET, amyloid PET, and tau PET. Dr. Jack’s group serves as the MR center for many large multi-site observational and interventional studies.